منابع مشابه
Drug discovery for alopecia: gone today, hair tomorrow.
INTRODUCTION Hair loss or alopecia affects the majority of the population at some time in their life, and increasingly, sufferers are demanding treatment. Three main types of alopecia (androgenic [AGA], areata [AA] and chemotherapy-induced [CIA]) are very different, and have their own laboratory models and separate drug-discovery efforts. AREAS COVERED In this article, the authors review the ...
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A group of genes in the tumour necrosis factor signalling pathway are mutated in humans and mice with ectodermal dysplasias--a failure of hair and tooth development. A mutation has now been identified in one of these genes, ectodysplasin-A receptor, in the teleost fish Medaka, that results in a failure of scale formation.
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chromosome 19q13.2, contains 23 exons, and expresses a 2.4 kb transcript. XPD is a 760 amino acid protein that contains 7 distinctive helicase motifs and functions in vitro as a 5Ј-to-3Ј helicase that unwinds DNA in the vicinity of damaged sites. Early studies indicated XP-D cells had a severe defect in the excision of the major UV light-induced photoproducts from DNA, the [5-5,6-6] cyclobutane...
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Despite the variations of length and type of hair (vellus or terminal), the growth of human hair in all body sites is cyclic. Phases of active hair growth, or anagen, are separated by periods of quiescence, or telogen. The duration of both phases varies greatly depending on the body site. Whether hairs are in anagen/telogen at the time of hair removal is important because only anagen hairs are ...
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Alzheimer's disease is the most common and well - known cause of dementia, as a progressive, irreversible brain disorder that affects cognitive function, personality, thought, perception and behaviour. Alzheimer's disease is the fourth leading cause of death in western countries. Interesting to know that this disease was unknown in medical community till 100 years ago and had no name. Dr. Alois...
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ژورنال
عنوان ژورنال: BioScience
سال: 2000
ISSN: 0006-3568
DOI: 10.1641/0006-3568(2000)050[0303:ht]2.3.co;2